The bank has been converting the former Thomas Cook travel agents into a fully connected work and meeting venue with the help of JT’s ultra-fast Wi-Fi services. “It’s interesting, but are we suggesting that coffee is a cure? Absolutely not,” he cautions.JT has been at the heart of Santander International’s successful move to Charing Cross providing its world class Wi-Fi for the bank’s new work café. “What this study does is take the epidemiological evidence and try to refine it and to demonstrate that there are indeed components within coffee that are beneficial to warding off cognitive decline,” says Dr. Mancini stresses that before they can add phenylindanes as a treatment option for neurodegenerative conditions, they need to conduct a lot more research on how these compounds would work in a therapeutic context. If you have a complicated compound, it’s nicer to grow it in a crop, harvest the crop, grind the crop out and extract it than try to make it.”Īt the same time, however, Dr. “Mother Nature is a much better chemist than we are and Mother Nature is able to make these compounds. Mancini adds.įor the researchers, another exciting aspect of this discovery is that these coffee compounds are natural and do not require synthesis in the laboratory, which makes them less complicated to produce. “The next step would be to investigate how beneficial these compounds are, and whether they have the ability to enter the bloodstream, or cross the blood-brain barrier,” Dr. In the future, the researchers aim to conduct more detailed investigations on the properties of phenylindanes, and their effects on the body once ingested. “It’s the first time anybody’s investigated how phenylindanes interact with the proteins that are responsible for Alzheimer’s and Parkinson’s,” says Dr. This suggests that dark roasted coffee - whether regular or decaf - has the strongest protective effect on the brain. It appears that a longer roasting time causes the coffee beans to produce more phenylindanes. Very interesting, we were not expecting that,” Dr. These are toxic proteins, of which the excessive buildup in the brain is a key factor in neurodegenerative conditions such as Alzheimer’s and Parkinson’s disease. It is the phenylindanes, rather than any other coffee-related compounds, that seem to inhibit the amalgamation of tau and beta-amyloid. Gradually, all the links fell into place, as the researchers started focusing on a set of compounds called phenylindanes, which form during the process of roasting coffee beans and lend coffee its bitter flavor. Ross Mancini, a research fellow in medicinal chemistry. So we observed early on that its protective effect could not be due to caffeine,” says study co-author Dr. “The caffeinated and decaffeinated dark roast both had identical potencies in our initial experimental tests. In the current study, the researchers decided to look into the effects of three types of coffee: caffeinated dark roast, caffeinated light roast, and decaffeinated dark roast. Weaver and team’s findings - published in the journal Frontiers in Neuroscience - suggest that the key to coffee’s brain-protecting benefits lie not in its caffeine content, but in the existence of compounds released in the process of roasting the coffee beans. “But we wanted to investigate why that is - which compounds are involved and how they may impact age-related cognitive decline,” he adds.ĭr. Donald Weaver, who is co-director of the Krembil Brain Institute. “Coffee consumption does seem to have some correlation to a decreased risk of developing Alzheimer’s disease and Parkinson’s disease,” notes Dr. How does this happen, and what is it about coffee that is so beneficial to cognitive health? These are some questions that a new study from the Krembil Brain Institute - part of the Krembil Research Institute in Toronto, Canada - aims to answer. One of these benefits is that coffee seems to protect the brain against cognitive impairments and boost thinking skills. While drinking coffee can bring both benefits and risks for a person’s health, a 2016 study from the University of Ulster in Coleraine, United Kingdom, concluded that the health benefits of moderate coffee consumption “clearly outweigh” the potential risks.
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